Iran's top negotiator Mohammad Baqer Qalibaf said on Wednesday that if Iran did not benefit from its memorandum of understanding with the U.S., "we have no reason to adhere to such an understanding."

Iran's national security depends on maintaining "Iranian arrangements" in the Strait of Hormuz, Qalibaf added in a statement posted on Telegram.

He said Iran's approach to its war with the US and negotiations to end it should be based on national interests, national security and a long-term perspective, adding that Tehran had no choice but to rely on its own strength.

The statements come in the wake of renewed crossfire between US and Iran that has left the interim ceasefire agreement signed by both the nations in tatters.

The back-and-forth started after Iran attacked a vessel in the Strait of Hormuz and the US retaliated with strikes on Iran, prompting the Islamic republic to target US military bases across Gulf nations.